92. Steele AD, Madhi SA, Louw CE, Bo P, Tumbo JT, Werner CM, De Vos B, Bicer C, Delem A, Han HH.  Safety, reactogenicity and immunogenicity of human rotavirus vaccine RIX4414 in HIV-positive infants in South Africa. Pediatr Infect Dis J; 2011 Feb;30(2):125-30.

93. Madhi SA,  Maskew M, Koen A, Kuwanda L, Besselaar TG, Naidoo D, Cohen C; Cutland C, Sanne I. Trivalent inactivated influenza vaccine in African adults infected with human immunodeficient virus: double blind, randomised clinical trial of efficacy, immunogenicity and safety. Clin Infect Dis; 2011 Jan 1;52(1):128-37

94. Rouphael N, Steyn S, Bangert M, Sampson JS, Adrian P, Madhi SA, Klugman KP, Ades AW. Use of Two Pneumococcal Common Protein real-time PCR assays in healthy children colonized with Streptococcus pneumoniae. Diag Microb Infect Dis; 2011: 70: 215-9.

95. Fairlie L, Beylis NC, Reubenson G, Moore DP, Madhi SA. High prevalence of childhood multi-drug resistant tuberculosis in Johannesburg, South Africa: a cross sectional study. BMC Infect Dis. 2011. 11:28.                                                                                                             

96. Madhi SA, Cutland C, Jones S, Groome M, Ortiz E. Immunogenicity and safety of an acellular pertussis, diphtheria, tetanus, inactivated poliovirus, Hib-conjugate combined vaccine (Pentaxim) and monovalent hepatitis B vaccine at 6, 10 and 14 weeks of age in infants in South Africa. S Afr Med J. 2011 Feb;101(2):126-31.

97. Webster J, Theodoratou E, Nair H, Seong AC, Zgaga L, Huda T, Johnson HL, Madhi S, Rubens C, Zhang JS, El Arifeen S, Krause R, Jacobs TA, Brooks AW, Campbell H, Rudan I. An evaluation of emerging vaccines for childhood pneumococcal pneumonia. BMC Public Health. 2011 Apr 13;11 Suppl 3:S26.

98. Madzivhandila M, Adrian PV, Cutland CL, Kuwanda L, Schrag SJ, Madhi SA. Serotype distribution and invasive potential of group B streptococcus isolates causing disease in infants and colonizing maternal-newborn dyads. PLoS One. 2011 Mar 21;6(3):e17861.

99. Madhi SA, Mitha I, Cutland C, Groome M, Santos-Lima E. Immunogenicity and safety of an investigational fully liquid hexavalent combination vaccine versus licensed combination vaccines at 6, 10, and 14 weeks of age in healthy South African infants. Pediatr Infect Dis J. 2011 Apr;30(4):e68-74.

100. Nunes MC, von Gottberg A, de Gouveia L, Cohen C, Moore DP, Klugman KP, Madhi SA. The impact of antiretroviral treatment on the burden of invasive pneumococcal disease in South African children: a time series analysis. AIDS. 2011 Feb 20;25(4):453-62.

101. Kasambira TS, Shah M, Adrian PV, Holshouser M, Madhi SA, Chaisson RE, Martinson NA, Dorman SE. QuantiFERON®-TB Gold In-Tube for the detection of Mycobacterium tuberculosis infection in children with household tuberculosis contact. Int J Tuberc Lung Dis; 2011: 15(5):628–634

102. Madhi SA, Nachman S, Violari A, Kim S, Cotton MF, Bobat R, Jean-Philippe P, McSherry G, Mitchell C; P1041 Study Team. Primary isoniazid prophylaxis against tuberculosis in HIV-exposed children. N Engl J Med. 2011 Jul 7;365(1):21-31.

103. Klugman KP, Madhi SA, Adegbola RA, Cutts F, Greenwood B, Hausdorff WP. Timing of serotype 1 pneumococcal disease suggests the need for evaluation of a booster dose. Vaccine 29 (2011) 3372–3373

104. Rees H, Madhi SA. Will the Decade of Vaccines mean business unusual? Lancet; 2011; 378: 382-5.                                                                                                                                         

105. Visser A, Moore DP, Whitelaw A, Lowman W, Kantor G, Hoosen A, Madhi SA, Brink A, van den Bergh D, Devenish L, Moodley P, Apalata T, Duse AG, Gelband H.  Part VII. Antibiotic Resistance Interventions: Part VII. S. Afr Med J. 2011; 101 (8): 587-95.                                                                                             

106. Nunes M, Madhi SA. Review on the safety and immunogenicity of PCV-13 in infants and toddlers. Exp Rev Vaccines, 2011; 10; 951-979.

107. Plotkin S, Liese J, Madhi SA, Oritz E. A DTaP-IPV/PRP-T vaccine (Pentaxim™): A review of 16 years of clinical experience. Exp Rev Vaccines, 2011; 10; 975-999.

108. Hainline C, Taliep R, Sorour G, Nachman S, Rabie H, Dobbels E, Janse van Rensburg A, Cornell C, Violari A, Madhi SA and Cotton MF. Early        antiretroviral therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy: Evidence from the        Children with HIV Early Antiretroviral Therapy (CHER). BMC Research Notes; MS : 1985179335553860

109. Punpanich W; Groome M; Muhe L; Qazi SA; Madhi SA. Systematic review on the etiology and antibiotic treatment of pneumonia in HIV-infected children. Pediatr Infect Dis J; 2011; 30 (10): e192-202.

110. Nair H, Brooks AW, Katz M, Roca A, Berkley JA, Madhi SA, Simmerman JM, Gordon A, Sato M, Howie S, Krishnan A, Ope M, Lindblade KA, Carosone-Link P, Lucero M, Ochieng W, Kamimoto L, Dueger E, Bhat N, Vong S, Theodoratou E, Chittaganpitch M, Chimah O, Balmaseda A, Buchy P, Harris E, Evans V, Katayose M, Gaur B, O'Callaghan-Gordo C, Goswami D, Arvelo W, Venter M, Briese T, Tokarz R, Widdowson M A, Mounts AW, Breiman RF, Feikin DR, Klugman KP, Olsen SJ, Gessner BD, Wright PF, Rudan I, Broor S, Simoes EA, Campbell H. The global burden of respiratory infections due to seasonal influenza in 2 young children: a systematic review and meta-analysis. Lancet; 2011; 378: 1917-30.                                                                                               

111. Rabie H, Violari A, Duong T, Madhi SA, Josipovic D, Innes S, Dobbels E, Lazarus E, Panchia R, Babiker AG, Gibb DM, Cotton MF for the CHER team. Early antiretroviral treatment reduces risk of bacille Calmette-Guérin immune reconstitution adenitis.  Int J Tuberc Lung Dis; 2011 15(9):1–7.

112. Madhi SA, Violari A, Klugman KP, Lin G, McIntyre JA, Gottberg AV, Jean-Philippe P, Cotton MF, Adrian P on behalf of the CIPRA 4 team. Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary series of immunization. Vaccine; 2011. 29 (40) :6994-7001.

113. Shah M. Kasambira TS, Adrian PV, Madhi SA, Martinson NA, Dorman SE. Longitudinal Analysis of QuantiFERON-TB Gold In-Tube in Children        with Adult Household Tuberculosis Contact in South Africa: A Prospective Cohort Study. PLoS One; 2011; 6:e26787.

114. Nunes M, von Gottberg A, de Gouveia L, Cohen C, Kuwanda L, Karstaedt A S,Klugman KP, Madhi SA. Persistent high burden of invasive         pneumococcal disease in South African HIV-infected adults in the era of an antiretroviral treatment program. PlosOne; 2011: 11: e27929

115. Groome M, Madhi SA. Five-year Cohort Study on the Burden of Hospitalisation for Acute Diarrhoeal Disease in African HIV-infected and HIV-uninfected Children: Potential Benefits of Rotavirus Vaccine. Vaccine . 2012; 30(Suppl1): A173-8.

116. Madhi SA, Kirsten M, Louw C, Bos P, Aspinall S, Bouckenooghe A, Neuzil KM, Steele AD. Efficacy and immunogenicity of two or three dose rotavirus-vaccine regimen in South African children over two consecutive rotavirus-seasons: a randomized, double-blind, placebo-controlled trial. Vaccine. 2012; 30(Suppl1): A44-51.

117. Nunes MC, Madhi SA. Review: Safety, immunogenicity and efficacy of pneumococcal conjugate vaccine in HIV-infected individuals. Human Vacc Immuno. 2012 ; 8(2): 161-73.

118. Madhi SA, Cutland C, Jones S, Groome M, Ortiz E. One-year post-primary antibody persistence and booster immune response to a DTaP-IPV//PRP~T Vaccine (Pentaxim®) given at 18-19 months of age in South African children primed at 6, 10 & 14 weeks of age with the same vaccine. S Afr Med J. 2011; 101: 879-883.

119. Groome MJ, Albrich WC, Wadula J, Khoosal M, Madhi SA. Community-onset Staphylococcus aureus bacteraemia in hospitalised African children: high incidence in HIV-infected children and high prevalence of multidrug resistance. Pediatr Int Child Health. 2012; 32(3): 140-6.  

120. Son M, Weiser J, Shchepetov M, Adrian P, Madhi SA, de Gouveia L, von Gottberg A, Klugman K and Dawid S. Conserved Mutations in the Pneumococcal Bacteriocin Transporter Gene, blpA, Results in a Complex Population Consisting of Producers and Cheaters. mBio 2011; 2(5): e00179-11.

121. Wiysonge CS, Armah GE, Madhi SA, Were F, Kitaka SB, Akoua-Koffi C, et al. The African Vaccine-Preventable Diseases Network: a vaccine advocacy initiative. Pan Afr Med J.; 2011; 8: 24.

122. Jaspan HB, Myer L, Madhi SA, Violari A, Gibb G, Stevens WS, Dobbels E, and Cotton MF. Utility of clinical parameters to identify HIV infection in infants below ten weeks of age in South Africa: a prospective cohort study. BMC Pediatrics. 2011; 11:104.

123. Nzenze S, Klugman KP, Madhi SA. The potential impact of the 13-valent conjugate pneumococcal vaccine on antibiotic resistance in pneumococci. South Afr J Epidemiol Infect 2011;26(4)(Part II):253-258.

124. Schrag S, Baker C, Beall B, Boslego J, Carlone G, Klugman KP, Madhi SA, McGee  L, Messonnier N, Neuzil K, Schuchat A, Romero-Steiner S, Verani J, Whitney C, Zaidi A (2011). Group B streptococcal vaccine for resource-poor countries. Lancet, 2011; 378 pp. 11 - 12.

125. Visser A, Moore DP, Whitelaw A, Lowman W, Kantor G, Hoosen A, Madhi SA, Brink A, van den Bergh D, Devenish L, Moodley P, Apalata T, Duse AG, Gelband H. Part V: Interventions against antimicrobial resistance. S. Afr Med J; 2011: 101 (8 Pt2): 587-95.


126. Albrich WC, Madhi SA, Adrian PV, van Niekerk N, Mareletsi T, Cutland C, Wong M,Khoosal M, Karstaedt A, Zhao P, Deatly A, Sidhu M, Jansen KU, Klugman KP. Use of a  rapid test of pneumococcal colonization density to diagnose pneumococcal pneumonia.

       Clin Infect Dis, 2012; 54:601-9.

127.von Gottberg A, Cohen C, Whitelaw A, Chhagan M, Flannery B, Cohen AL, de Gouveia L, du Plessis M, Madhi SA, Klugman KP. Invasive disease due to Haemophilus influenzae type b ten years after routine vaccination in South Africa, 2003-2009. Vaccine; 2012: 30: 565-71.

128. Robertson A, Firth GB, Truda C, Ramdass DA, Groome MJ, Madhi SA. Epidemiology of acute osteo-articular sepsis in a setting with a high prevalence of pediatric HIV infection. J Pediatr Ortho; 2012; 32 (2):215-9.129. Reed C, Madhi SA, Klugman KP, Kuwanda L, Ortiz JR, Finelli L, Fry AM. Development of the Respiratory Index of Severity in Children (RISC) score among young children with  

        respiratory infections in South Africa. PlosOne. 2012; 7: e27793.

130. Omer SB, Bednarczyk R, Madhi SA, Klugman KP. Benefits to mother and child of influenza vaccination during pregnancy. Hum Vaccin Immunother. 2012; 8(1):130-7.

131. Hesseling AC, Kim S, Madhi SA,  Nachman S, Schaaf HS, Violari A, VictorTC, McSherry G, Mitchell C, Cotton MF for the IMPAACT P1041 Team. High prevalence of drug resistance among HIV-exposed and infected children on a tuberculosis prevention trial. Int J Tuberc Lung Dis. 2012; 16 (2):192-5.

132. Dagnew AF, Cunnington MC, Dube Q, Edwards MS, French N, Heyderman RS, MadhiSA, Slobod K, Clemens SUA. Understanding variation in neonatal Group B Streptococcal disease incidence in developing countries. Clin Infect Dis. 2012; 55: 91-102.

133. Graham SM, Ahmed T, Amanullah F, Browning R, Cardenas V, Casenghi M, Cuevas LE, Gale M, Gie RP, Grzemska M, Handelsman E, Hatherill M,  Hesseling AC, Jean-Philippe P, Kampmann B, Kabra SK, Lienhardt C, Lighter-Fisher J, Madhi SA, Makhene M, Marais BJ, McNeeley DF, Menzies H, Mitchell C, Modi S, Mofenson L, Musoke P, Nachman S, Powell C, Rigaud M, Rouzier V, Starke JR, Swaminathan S, Wingfield C. Evaluation of TB diagnostics in children: Proposed clinical case definitions for classification of intra-thoracic tuberculosis disease. Consensus from an Expert Panel.  J Infect Dis. 2012; 205 (Supp2); S199-208.

  134. Levine OS, O'Brien KL, Deloria-Knoll M, Murdoch DR, Feikin DR, Deluca AN, Driscoll AJ, Baggett HC, Brooks WA, Howie SR, Kotloff KL, Madhi SA, Maloney SA, Sow S, Thea DM, Scott JA. The pneumonia etiology research for child health project: a 21st century childhood pneumonia etiology study. Clin Infect Dis. 2012 ;54 Suppl 2:S93-S101.

135. Schrag SJ, Cutland CL, Zell ER, Kuwanda L, Buchmann E,  Velaphi SC,  Groome MJ, Madhi SA. Risk factors for neonatal sepsis and perinatal death among infants enrolled in the Prevention of Perinatal Sepsis Trial, Soweto, South Africa. Pediatr Infect Dis J; 2012, 2012, 31 (8): 821-6.

136. Punpanich W; Groome M; Muhe L; Qazi SA; Madhi SA. Antibiotic and systemic therapies for pneumonia in Human Immunodeficiency Virus (HIV)-infected and HIV-exposed children: A systematic review. J Infect Dev Countries; 2012; 6 (2): 109-19.

137. Sinha A, Kim S, Ginsberg G, Franklin H, Kohberger R, Strutton D, Madhi SA, Griffiths UK, Klugman KP. Economic burden of acute lower respiratory tract infection in South African children. Paediat Int Child Health. 2012; 32 (2): 65-73.

138. Kiser JJ, Zhu R, D’Argenio DZ, Cotton M, Bobat R, McSherry G, Madhi S, Carey V, Seifart H, Werely C, Fletcher CV.  Isoniazid pharmacokinetics and dosing in South African infants.  Therapeutic Drug Monitoring 2012; 36 (4): 446-451.

139. Laughton B, Cornell M, Grove D, Kidd M, Springer PE, Dobbels E, Janse van Rensburg A, Violari A, Babiker AG, Madhi SA, Jean-Phillipe P, Gibb DM, Cotton MF. Early antiretroviral therapy improves neurodevelopmental outcomes in infants. AIDS; 2012; 26 (13): 1685-1690.

140. Madhi SA, Cohen C, von Gottberg A. Introduction of pneumococcal conjugate vaccine into the public immunization program in South Africa: translating research into policy. Vaccine. 2012, 30(Suppl3): C21-7.

141. Wiysonge SC, Ngcobo NJ, Prakash JM, Madhi SA, Schoub BD, Hawkridge A, Shey MS, Hussey GD. Advances in childhood immunisation in South Africa: where to now? Programme managers views and evidence from systematic reviews. BMC Public Health. 2012. 12: 578 (MS: 2002286525661538)

142. Cutland CL, Schrag SJ, Zell ER, Kuwanda L, Buchmann E, Velaphi SC, Groome MJ,  Adrian PV, Madhi SA. Maternal HIV infection and vertical transmission of pathogenic bacteria. Pediatrics; 2012; 130 (3): 1-10.

143. Tokarz R, Firth C, Madhi SA, Howie SR, Wu WY, Sall AA, Haq S, Briese T, Lipkin WI. Worldwide emergence of multiple clades of enterovirus 68. J Gen Virol. 2012; 93 (9):  1952-8.

144. Steele AD, Neuzil KM, Cunliffe NA, Madhi SA, Bos P,  Ngwira B, Witte D, Todd S, Louw C, Kirsten M, Aspinall S, jan van Doorn L, Bouckenooghe L, Suryakiran PV, Han HH. Human rotavirus vaccine Rotarix™ provides protection against diverse circulating rotavirus strains in African infants: a randomized controlled trial. BMC Infect Dis 2012; 12: 213 (e1296340893655593).

145. Cohen C, Simonsen L, Sample J, Kang JW, Miller M, Madhi SA, Campsmith M, Viboud C. Influenza-related mortality among adults aged 25-54 years with AIDS in South Africa and the United States of America. Clin Infect Dis 2012. 55(7): 996-1003.

146. Venter M, Naidoo D, Pretorius M, Treurnicht F, Buys A, McAnerney J, Blumberg L, Madhi SA, Cohen C, Schoub B. Evolutionary dynamics of Pandemic H1N1/09 in South Africa from 2009-2010. J Infect Dis 2012; 206 (suppl1): S166-S172.

147. Pretorius MA, Madhi SA, Cohen C, Naidoo D, Groome M, Moyes J, Buys A, Walaza S, Dawood H, Chhagan M, Haffejee S, Kahn K, Puren A, Venter M. Prevalence of respiratory viral co-infections in South Africans hospitalized for Severe Acute Respiratory Illness during 2009 and 2010. J Infect Dis 2012. 206 (Suppl1): S59-65.

148. Moore D, Dagan R, Madhi SA. Respiratory viral and pneumococcal co-infection of the respiratory tract: implications of pneumococcal vaccination. Exp Rev Resp Med. 2012. 6(4): 451-65.


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